Varaico: Literature-Extracted Genetic Variants

Gene:IDH2
Variant:p.N88S

IDH2

2,456 papers

RefSeq Summary

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor...

Pfam Domains

Iso_dhaa 45–441UCSCIsocitrate/isopropylmalate dehydrogenase

Gene Aliases

HGNC Name

isocitrate dehydrogenase (NADP(+)) 2

HGNC Alias Symbol

IDH-2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_002168.4
p.N88S
c.263A>G
Surrounding Variants
1 paper
NM_002168.4
p.R89C
c.265C>T
1 paper
NM_002168.4
p.P87P
c.261A>G
2 papers
NM_002168.4
p.R89H
c.266G>A
1 paper
NM_002168.4
p.G85_L86del2
c.253_257del6
1 paper
NM_002168.4
p.D90N
c.268G>A
1 paper
NM_002168.4
p.L86P
c.257T>C
1 paper
NM_002168.4
p.G85E
c.254G>A
1 paper
NM_002168.4
p.Q91delFs
c.271delG
1 paper
NM_002168.4
p.Q91H
c.273G>C
1 paper
NM_002168.4
p.G85R
c.253G>C
1 paper
NM_002168.4
p.G85R
c.253G>A
1 paper
NM_002168.4
p.T92P
c.274A>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."