Varaico: Literature-Extracted Genetic Variants

IFNAR1

203 papers

RefSeq Summary

The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus pro...

Pfam Domains

Tissue_facaa 4–115UCSCTissue factor

Interfer-bindaa 126–224UCSCInterferon-alpha/beta receptor, fibronectin type III

Interfer-bindaa 330–430UCSCInterferon-alpha/beta receptor, fibronectin type III

Gene Aliases

HGNC Name

interferon alpha and beta receptor subunit 1

HGNC Alias Symbol

IFRC

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

8 papers

NM_000629.3

p.W261*

c.783G>A

Surrounding Variants

8 papers

NM_000629.3

p.W261*

c.782G>A

1 paper

NM_000629.3

p.A253fs

c.757_758fs

1 paper

NM_000629.3

p.A253delFs

c.757delG

2 papers

NM_000629.3

p.Y244C

c.731A>G

1 paper

NM_000629.3

p.N243T

c.728A>C

1 paper

NM_000629.3

p.P231S

c.691C>T

1 paper

NM_000629.3

p.L229R

c.686T>G

1 paper

NM_000629.3

p.V225fs

c.673_674fs

4 papers

NM_000629.3

p.V225Splc

c.674-1G>A

1 paper

NM_000629.3

p.V225Splc

c.674-1G>T

5 papers

NM_000629.3

p.V225Splc

c.674-2A>G

1 paper

NM_000629.3

p.V225Splc

c.674-70T>C