Varaico: Literature-Extracted Genetic Variants

IFNAR1

203 papers

RefSeq Summary

The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus pro...

Pfam Domains

Tissue_facaa 4–115UCSCTissue factor

Interfer-bindaa 126–224UCSCInterferon-alpha/beta receptor, fibronectin type III

Interfer-bindaa 330–430UCSCInterferon-alpha/beta receptor, fibronectin type III

Gene Aliases

HGNC Name

interferon alpha and beta receptor subunit 1

HGNC Alias Symbol

IFRC

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000629.3

p.Y481F

c.1442A>T

Surrounding Variants

1 paper

NM_000629.3

p.Y481fs

c.1441_1442fs

1 paper

NM_000629.3

p.E480_Y481Splc

c.1441-1G>A

1 paper

NM_000629.3

p.E484K

c.1450G>A

1 paper

NM_000629.3

p.E484Q

c.1450G>C

1 paper

NM_000629.3

p.E496A

c.1487A>C

1 paper

NM_000629.3

p.E497A

c.1490A>C

1 paper

NM_000629.3

p.E500A

c.1499A>C

1 paper

NM_000629.3

p.K501Q

c.1501A>C

1 paper

NM_000629.3

p.K501R

c.1502A>G

1 paper

NM_000629.3

p.K525R

c.1574A>G

1 paper

NM_000629.3

p.K526R

c.1577A>G

1 paper

NM_000629.3

p.Y527F

c.1580A>T