Varaico: Literature-Extracted Genetic Variants

IGF2BP2

1,233 papers

RefSeq Summary

This gene encodes a protein that binds the 5' UTR of insulin-like growth factor 2 (IGF2) mRNA and regulates its translation. It plays an important role in metabolism and variation in this gene is asso...

Pfam Domains

RRM_1aa 5–70UCSCRNA recognition motif

RRM_1aa 84–151UCSCRNA recognition motif

KH_1aa 195–260UCSCKH domain

Gene Aliases

HGNC Name

insulin like growth factor 2 mRNA binding protein 2

HGNC Alias Symbols

IMP-2; p62; P62

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006548.6

p.T330K

c.989C>A

Surrounding Variants

1 paper

NM_006548.6

p.G329V

c.986G>T

1 paper

NM_006548.6

p.G329S

c.985G>A

1 paper

NM_006548.6

p.E332K

c.994G>A

1 paper

NM_006548.6

p.T326A

c.976A>G

1 paper

NM_006548.6

p.I325insFs

c.973dupA

1 paper

NM_006548.6

p.T324delFs

c.972delG

1 paper

NM_006548.6

p.T324delFs

c.970_971delGT

1 paper

NM_006548.6

p.R323S

c.969A>T

1 paper

NM_006548.6

p.R323S

c.969A>C

1 paper

NM_006548.6

p.R323_T324insFs

c.969_970insTT

1 paper

NM_006548.6

p.S336delFs

c.1007_1008delAC

2 papers

NM_006548.6

p.E322K

c.964G>A