Varaico: Literature-Extracted Genetic Variants

IGF2BP2

1,233 papers

RefSeq Summary

This gene encodes a protein that binds the 5' UTR of insulin-like growth factor 2 (IGF2) mRNA and regulates its translation. It plays an important role in metabolism and variation in this gene is asso...

Pfam Domains

RRM_1aa 5–70UCSCRNA recognition motif

RRM_1aa 84–151UCSCRNA recognition motif

KH_1aa 195–260UCSCKH domain

Gene Aliases

HGNC Name

insulin like growth factor 2 mRNA binding protein 2

HGNC Alias Symbols

IMP-2; p62; P62

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006548.6

p.P183A

c.547C>G

Surrounding Variants

3 papers

NM_006548.6

p.G184_G185insFs

c.552_553ins4

1 paper

NM_006548.6

p.G184delFs

c.551delC

1 paper

NM_006548.6

p.T186_S187insFs

c.558_559insC

1 paper

NM_006548.6

p.Q188*

c.562C>T

3 papers

NM_006548.6

p.S175delFs

c.525delA

1 paper

NM_006548.6

p.I192T

c.575T>C

1 paper

NM_006548.6

p.D173Y

c.517G>T

1 paper

NM_006548.6

p.G172G

c.516G>C

1 paper

NM_006548.6

p.D193D

c.579T>C

4 papers

NM_006548.6

p.R171C

c.511C>T

3 papers

NM_006548.6

p.Q170fs

c.508_509fs

1 paper

NM_006548.6

p.L196L

c.586C>T