Varaico: Literature-Extracted Genetic Variants

IGF2BP2

1,233 papers

RefSeq Summary

This gene encodes a protein that binds the 5' UTR of insulin-like growth factor 2 (IGF2) mRNA and regulates its translation. It plays an important role in metabolism and variation in this gene is asso...

Pfam Domains

RRM_1aa 5–70UCSCRNA recognition motif

RRM_1aa 84–151UCSCRNA recognition motif

KH_1aa 195–260UCSCKH domain

Gene Aliases

HGNC Name

insulin like growth factor 2 mRNA binding protein 2

HGNC Alias Symbols

IMP-2; p62; P62

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006548.6

p.Y148*

c.444C>A

Surrounding Variants

1 paper

NM_006548.6

p.S149A

c.445T>G

2 papers

NM_006548.6

p.S149S

c.447C>A

1 paper

NM_006548.6

p.Y148_S149delFs

c.442_446del5

1 paper

NM_006548.6

p.S149_F150delFs

c.447_448delAG

1 paper

NM_006548.6

p.E146D

c.438G>T

1 paper

NM_006548.6

p.E146insFs

c.437dupA

1 paper

NM_006548.6

p.E146D

c.438G>C

1 paper

NM_006548.6

p.K151N

c.453G>T

1 paper

NM_006548.6

p.I152T

c.455T>C

1 paper

NM_006548.6

p.Q144H

c.432G>T

1 paper

NM_006548.6

p.Q144*

c.430C>T

1 paper

NM_006548.6

p.L140_G142delFs

c.420_426del7