Varaico: Literature-Extracted Genetic Variants

IGFBP7

210 papers

RefSeq Summary

This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and mod...

Pfam Domains

IGFBPaa 32–87UCSCInsulin-like growth factor binding protein

Kazal_2aa 108–156UCSCKazal-type serine protease inhibitor domain

I-setaa 160–265UCSCImmunoglobulin I-set domain

Gene Aliases

HGNC Name

insulin like growth factor binding protein 7

HGNC Alias Symbols

MAC25; IGFBP-7; PSF; FSTL2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001553.3

p.T125A

c.373A>G

Surrounding Variants

1 paper

NM_001553.3

p.G124D

c.371G>A

2 papers

NM_001553.3

p.G124S

c.370G>A

1 paper

NM_001553.3

p.P118T

c.352C>A

2 papers

NM_001553.3

p.A135T

c.403G>A

1 paper

NM_001553.3

p.A140P

c.418G>C

1 paper

NM_001553.3

p.A140T

c.418G>A

1 paper

NM_001553.3

p.G109D

c.326G>A

1 paper

NM_001553.3

p.E141A

c.422A>C

1 paper

NM_001553.3

p.G144E

c.431G>A

1 paper

NM_001553.3

p.G104S

c.310G>A

1 paper

NM_001553.3

p.G103D

c.308G>A

1 paper

NM_001553.3

p.A98G

c.293C>G