Varaico: Literature-Extracted Genetic Variants

IGFBP7

210 papers

RefSeq Summary

This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and mod...

Pfam Domains

IGFBPaa 32–87UCSCInsulin-like growth factor binding protein

Kazal_2aa 108–156UCSCKazal-type serine protease inhibitor domain

I-setaa 160–265UCSCImmunoglobulin I-set domain

Gene Aliases

HGNC Name

insulin like growth factor binding protein 7

HGNC Alias Symbols

MAC25; IGFBP-7; PSF; FSTL2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001553.3

p.S29A

c.85T>G

Surrounding Variants

1 paper

NM_001553.3

p.S26C

c.77C>G

1 paper

NM_001553.3

p.P22P

c.66C>G

1 paper

NM_001553.3

p.P22R

c.65C>G

1 paper

NM_001553.3

p.L20P

c.59T>C

1 paper

NM_001553.3

p.L17P

c.50T>C

1 paper

NM_001553.3

p.P42T

c.124C>A

1 paper

NM_001553.3

p.G15R

c.43G>C

1 paper

NM_001553.3

p.G15R

c.43G>A

1 paper

NM_001553.3

p.A14G

c.41C>G

1 paper

NM_001553.3

p.A14D

c.41C>A

1 paper

NM_001553.3

p.A13G

c.38C>G

1 paper

NM_001553.3

p.P44P

c.132C>A