Varaico: Literature-Extracted Genetic Variants

IKBKE

234 papers

RefSeq Summary

IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene a...

Pfam Domains

Pkinaseaa 9–301UCSCProtein kinase domain

TBK1_ULDaa 308–393UCSCTANK binding kinase 1 ubiquitin-like domain

TBK1_CCD1aa 400–646UCSCTANK-binding kinase 1 coiled-coil domain 1

Gene Aliases

HGNC Name

inhibitor of nuclear factor kappa B kinase subunit epsilon

HGNC Alias Symbols

IKKE; IKK-i; KIAA0151

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014002.4

p.A160T

c.478G>A

Surrounding Variants

1 paper

NM_014002.4

p.F158_A161del0

c.472_483del12

1 paper

NM_014002.4

p.T156A

c.466A>G

1 paper

NM_014002.4

p.K154K

c.462G>A

1 paper

NM_014002.4

p.K154R

c.461A>G

1 paper

NM_014002.4

p.K154M

c.461A>T

1 paper

NM_014002.4

p.Y153F

c.458A>T

1 paper

NM_014002.4

p.Y153H

c.457T>C

2 papers

NM_014002.4

p.D167E

c.501T>A

1 paper

NM_014002.4

p.D167E

c.501T>G

1 paper

NM_014002.4

p.E168A

c.503A>C

1 paper

NM_014002.4

p.G149R

c.445G>A

1 paper

NM_014002.4

p.G149R

c.445G>C