Varaico: Literature-Extracted Genetic Variants

IKBKE

234 papers

RefSeq Summary

IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene a...

Pfam Domains

Pkinaseaa 9–301UCSCProtein kinase domain

TBK1_ULDaa 308–393UCSCTANK binding kinase 1 ubiquitin-like domain

TBK1_CCD1aa 400–646UCSCTANK-binding kinase 1 coiled-coil domain 1

Gene Aliases

HGNC Name

inhibitor of nuclear factor kappa B kinase subunit epsilon

HGNC Alias Symbols

IKKE; IKK-i; KIAA0151

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014002.4

p.M184I

c.552G>T

Surrounding Variants

1 paper

NM_014002.4

p.M184I

c.552G>A

1 paper

NM_014002.4

p.M184I

c.552G>C

3 papers

NM_014002.4

p.D183N

c.547G>A

1 paper

NM_014002.4

p.D183Y

c.547G>T

4 papers

NM_014002.4

p.R187Q

c.560G>A

1 paper

NM_014002.4

p.L180_H181Splc

c.541-5G>A

1 paper

NM_014002.4

p.R191*

c.571C>T

1 paper

NM_014002.4

p.Q195Q

c.585A>G

1 paper

NM_014002.4

p.H213N

c.637C>A

1 paper

NM_014002.4

p.A215T

c.643G>A

1 paper

NM_014002.4

p.S218G

c.652A>G

1 paper

NM_014002.4

p.P220L

c.659C>T