Varaico: Literature-Extracted Genetic Variants

IKBKE

234 papers

RefSeq Summary

IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene a...

Pfam Domains

Pkinaseaa 9–301UCSCProtein kinase domain

TBK1_ULDaa 308–393UCSCTANK binding kinase 1 ubiquitin-like domain

TBK1_CCD1aa 400–646UCSCTANK-binding kinase 1 coiled-coil domain 1

Gene Aliases

HGNC Name

inhibitor of nuclear factor kappa B kinase subunit epsilon

HGNC Alias Symbols

IKKE; IKK-i; KIAA0151

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014002.4

p.F224L

c.672T>G

Surrounding Variants

1 paper

NM_014002.4

p.F224L

c.672T>A

1 paper

NM_014002.4

p.F224L

c.670T>C

1 paper

NM_014002.4

p.F224V

c.670T>G

1 paper

NM_014002.4

p.P227S

c.679C>T

1 paper

NM_014002.4

p.R228W

c.682C>T

1 paper

NM_014002.4

p.R228Q

c.683G>A

2 papers

NM_014002.4

p.R229W

c.685C>T

1 paper

NM_014002.4

p.P220L

c.659C>T

1 paper

NM_014002.4

p.R229Q

c.686G>A

1 paper

NM_014002.4

p.N230_K231delFs

c.690_691delCA

1 paper

NM_014002.4

p.S218G

c.652A>G

1 paper

NM_014002.4

p.A215T

c.643G>A