Varaico: Literature-Extracted Genetic Variants

IKBKE

234 papers

RefSeq Summary

IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene a...

Pfam Domains

Pkinaseaa 9–301UCSCProtein kinase domain

TBK1_ULDaa 308–393UCSCTANK binding kinase 1 ubiquitin-like domain

TBK1_CCD1aa 400–646UCSCTANK-binding kinase 1 coiled-coil domain 1

Gene Aliases

HGNC Name

inhibitor of nuclear factor kappa B kinase subunit epsilon

HGNC Alias Symbols

IKKE; IKK-i; KIAA0151

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

7 papers

NM_014002.4

p.A602V

c.1805C>T

Surrounding Variants

1 paper

NM_014002.4

p.Q601H

c.1803A>C

1 paper

NM_014002.4

p.Y600H

c.1798T>C

1 paper

NM_014002.4

p.V597M

c.1789G>A

1 paper

NM_014002.4

p.G608S

c.1822G>A

1 paper

NM_014002.4

p.G608C

c.1822G>T

1 paper

NM_014002.4

p.K609R

c.1826A>G

1 paper

NM_014002.4

p.R612W

c.1834A>T

1 paper

NM_014002.4

p.R612Splc

c.1835+11C>T

1 paper

NM_014002.4

p.H583Y

c.1747C>T

1 paper

NM_014002.4

p.S582T

c.1745G>C

1 paper

NM_014002.4

p.F581L

c.1743C>A

1 paper

NM_014002.4

p.F581L

c.1743C>G