Varaico: Literature-Extracted Genetic Variants

IKBKE

234 papers

RefSeq Summary

IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene a...

Pfam Domains

Pkinaseaa 9–301UCSCProtein kinase domain

TBK1_ULDaa 308–393UCSCTANK binding kinase 1 ubiquitin-like domain

TBK1_CCD1aa 400–646UCSCTANK-binding kinase 1 coiled-coil domain 1

Gene Aliases

HGNC Name

inhibitor of nuclear factor kappa B kinase subunit epsilon

HGNC Alias Symbols

IKKE; IKK-i; KIAA0151

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

5 papers

NM_014002.4

p.G660E

c.1979G>A

Surrounding Variants

1 paper

NM_014002.4

p.A661V

c.1982C>T

1 paper

NM_014002.4

p.P667S

c.1999C>T

1 paper

NM_014002.4

p.P667R

c.2000C>G

1 paper

NM_014002.4

p.I668L

c.2002A>C

1 paper

NM_014002.4

p.I668L

c.2002A>T

1 paper

NM_014002.4

p.L645L

c.1935C>T

1 paper

NM_014002.4

p.R676Q

c.2027G>A

1 paper

NM_014002.4

p.K677R

c.2030A>G

1 paper

NM_014002.4

p.L680F

c.2038C>T

1 paper

NM_014002.4

p.K644_L645Splc

c.1932+2T>G

1 paper

NM_014002.4

p.V638L

c.1912G>C

1 paper

NM_014002.4

p.Q636Q

c.1908G>A