Varaico: Literature-Extracted Genetic Variants

IKBKE

234 papers

RefSeq Summary

IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene a...

Pfam Domains

Pkinaseaa 9–301UCSCProtein kinase domain

TBK1_ULDaa 308–393UCSCTANK binding kinase 1 ubiquitin-like domain

TBK1_CCD1aa 400–646UCSCTANK-binding kinase 1 coiled-coil domain 1

Gene Aliases

HGNC Name

inhibitor of nuclear factor kappa B kinase subunit epsilon

HGNC Alias Symbols

IKKE; IKK-i; KIAA0151

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

15 papers

NM_014002.4

p.P713L

c.2138C>T

Surrounding Variants

1 paper

NM_014002.4

p.P711S

c.2131C>T

1 paper

NM_014002.4

p.V710A

c.2129T>C

1 paper

NM_014002.4

p.V710I

c.2128G>A

1 paper

NM_014002.4

p.R706G

c.2116C>G

1 paper

NM_014002.4

p.R706W

c.2116C>T

1 paper

NM_014002.4

p.E705K

c.2113G>A

1 paper

NM_014002.4

p.R702H

c.2105G>A

1 paper

NM_014002.4

p.A694V

c.2081C>T

1 paper

NM_014002.4

p.K691R

c.2072A>G

1 paper

NM_014002.4

p.C687C

c.2061C>T

1 paper

NM_014002.4

p.Q684H

c.2052A>C

1 paper

NM_014002.4

p.Q684H

c.2052A>T