Varaico: Literature-Extracted Genetic Variants

Gene:IL10
Variant:p.E72K

IL10

1,561 papers

RefSeq Summary

The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It dow...

Pfam Domains

IL10aa 1–89UCSCInterleukin 10

Gene Aliases

HGNC Name

interleukin 10

HGNC Alias Symbols

CSIF; IL10A; IL-10

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000572.3
p.E72K
c.214G>A
Surrounding Variants
1 paper
NM_000572.3
p.D73N
c.217G>A
1 paper
NM_000572.3
p.L71M
c.211C>A
1 paper
NM_000572.3
p.D73A
c.218A>C
1 paper
NM_000572.3
p.D73insFs
c.218_219ins22
2 papers
NM_000572.3
p.L70*
c.209T>A
1 paper
NM_000572.3
p.L70L
c.208T>C
1 paper
NM_000572.3
p.S69P
c.205T>C
1 paper
NM_000572.3
p.S69T
c.205T>A
1 paper
NM_000572.3
p.E68D
c.204G>T
1 paper
NM_000572.3
p.E68D
c.204G>C
1 paper
NM_000572.3
p.E68K
c.202G>A
1 paper
NM_000572.3
p.L65_K67insFs
c.193_200dup8
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."