Varaico: Literature-Extracted Genetic Variants

Gene:IL10
Variant:p.L65M

IL10

1,561 papers

RefSeq Summary

The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It dow...

Pfam Domains

IL10aa 1–89UCSCInterleukin 10

Gene Aliases

HGNC Name

interleukin 10

HGNC Alias Symbols

CSIF; IL10A; IL-10

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000572.3
p.L65M
c.193T>A
Surrounding Variants
1 paper
NM_000572.3
p.L64F
c.192G>T
1 paper
NM_000572.3
p.L65_L66insFs
c.195_196insT
1 paper
NM_000572.3
p.L64L
c.190T>C
1 paper
NM_000572.3
p.N63K
c.189C>G
1 paper
NM_000572.3
p.N63K
c.189C>A
1 paper
NM_000572.3
p.K58_D62del0
c.172_186del15
1 paper
NM_000572.3
p.N63S
c.188A>G
1 paper
NM_000572.3
p.L65_K67insFs
c.193_200dup8
2 papers
NM_000572.3
p.K67K
c.201G>A
1 paper
NM_000572.3
p.E68K
c.202G>A
1 paper
NM_000572.3
p.D62N
c.184G>A
1 paper
NM_000572.3
p.L61L
c.183G>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."