Varaico: Literature-Extracted Genetic Variants

Gene:IL12B
Variant:p.L218_K219del1

IL12B

290 papers

RefSeq Summary

This gene encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer comp...

Pfam Domains

IL12p40_Caa 126–216UCSCCytokine interleukin-12p40 C-terminus

Gene Aliases

HGNC Name

interleukin 12B

HGNC Previous Symbol

NKSF2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_002187.3
p.L218_K219del1
c.653_655delTGA
Surrounding Variants
1 paper
NM_002187.3
p.K217_L218del1
c.650_652delGCT
1 paper
NM_002187.3
p.Y220*
c.660T>G
1 paper
NM_002187.3
p.Y220*
c.660T>A
1 paper
NM_002187.3
p.L218_Y220delins
c.653_660delinsCCAGATGG
1 paper
NM_002187.3
p.E221_N222insFs
c.663_664insTT
1 paper
NM_002187.3
p.N222fs
c.664_665fs
1 paper
NM_002187.3
p.E204_V212delins
c.612_635delinsAATTGAGTCTTAGAAAAGTTAAGC
11 papers
NM_002187.3
p.S226N
c.677G>A
1 paper
NM_002187.3
p.V210G
c.629T>G
1 paper
NM_002187.3
p.V210I
c.628G>A
1 paper
NM_002187.3
p.F228F
c.684C>T
1 paper
NM_002187.3
p.E209K
c.625G>A
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