Varaico: Literature-Extracted Genetic Variants

Gene:IL12B
Variant:p.I77V

IL12B

290 papers

RefSeq Summary

This gene encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer comp...

Pfam Domains

IL12p40_Caa 126–216UCSCCytokine interleukin-12p40 C-terminus

Gene Aliases

HGNC Name

interleukin 12B

HGNC Previous Symbol

NKSF2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_002187.3
p.I77V
c.229A>G
Surrounding Variants
1 paper
NM_002187.3
p.I77T
c.230T>C
1 paper
NM_002187.3
p.T76I
c.227C>T
1 paper
NM_002187.3
p.V79V
c.237C>T
3 papers
NM_002187.3
p.K80E
c.238A>G
1 paper
NM_002187.3
p.T74P
c.220A>C
1 paper
NM_002187.3
p.E81G
c.242A>G
1 paper
NM_002187.3
p.G83R
c.247G>C
1 paper
NM_002187.3
p.G83R
c.247G>A
2 papers
NM_002187.3
p.D84N
c.250G>A
1 paper
NM_002187.3
p.G70S
c.208G>A
1 paper
NM_002187.3
p.D84V
c.251A>T
1 paper
NM_002187.3
p.V68F
c.202G>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."