Varaico: Literature-Extracted Genetic Variants

Gene:IL12B
Variant:p.P39L

IL12B

290 papers

RefSeq Summary

This gene encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer comp...

Pfam Domains

IL12p40_Caa 126–216UCSCCytokine interleukin-12p40 C-terminus

Gene Aliases

HGNC Name

interleukin 12B

HGNC Previous Symbol

NKSF2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_002187.3
p.P39L
c.116C>T
Surrounding Variants
1 paper
NM_002187.3
p.P39A
c.115C>G
1 paper
NM_002187.3
p.D40G
c.119A>G
1 paper
NM_002187.3
p.Y38C
c.113A>G
1 paper
NM_002187.3
p.A41V
c.122C>T
1 paper
NM_002187.3
p.L35_D36insFs
c.104_107dup4
1 paper
NM_002187.3
p.W37G
c.109T>G
1 paper
NM_002187.3
p.W37R
c.109T>C
1 paper
NM_002187.3
p.W37R
c.109T>A
1 paper
NM_002187.3
p.P42T
c.124C>A
1 paper
NM_002187.3
p.L35insFs
c.105dupG
1 paper
NM_002187.3
p.D36insFs
c.106_107insT
1 paper
NM_002187.3
p.G43R
c.127G>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."