Varaico: Literature-Extracted Genetic Variants

IL17RA

243 papers

RefSeq Summary

Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The tran...

Pfam Domains

IL17R_fnIII_D1aa 35–188UCSCIL17RA/B, N-terminal domain

IL17R_fnIII_D2aa 199–303UCSCIL17RD, second fnIII domain

SEFIRaa 378–536UCSCSEFIR domain

Gene Aliases

HGNC Name

interleukin 17 receptor A

HGNC Previous Symbol

IL17R

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_014339.7

p.S55Splc

c.163+1G>A

Surrounding Variants

1 paper

NM_014339.7

p.T51M

c.152C>T

1 paper

NM_014339.7

p.N49D

c.145A>G

2 papers

NM_014339.7

p.G47A

c.140G>C

1 paper

NM_014339.7

p.G47R

c.139G>A

1 paper

NM_014339.7

p.G47R

c.139G>C

2 papers

NM_014339.7

p.S55insFs

c.164_165ins4

3 papers

NM_014339.7

p.C57fs

c.169_170fs

1 paper

NM_014339.7

p.C57Y

c.170G>A

1 paper

NM_014339.7

p.L58L

c.174G>C

1 paper

NM_014339.7

p.D60delFs

c.180delC

4 papers

NM_014339.7

p.R66*

c.196C>T

12 papers

NM_014339.7

p.R66Q

c.197G>A