Varaico: Literature-Extracted Genetic Variants

IL17RA

243 papers

RefSeq Summary

Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The tran...

Pfam Domains

IL17R_fnIII_D1aa 35–188UCSCIL17RA/B, N-terminal domain

IL17R_fnIII_D2aa 199–303UCSCIL17RD, second fnIII domain

SEFIRaa 378–536UCSCSEFIR domain

Gene Aliases

HGNC Name

interleukin 17 receptor A

HGNC Previous Symbol

IL17R

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_014339.7

p.C57fs

c.169_170fs

Surrounding Variants

1 paper

NM_014339.7

p.C57Y

c.170G>A

1 paper

NM_014339.7

p.L58L

c.174G>C

2 papers

NM_014339.7

p.S55insFs

c.164_165ins4

1 paper

NM_014339.7

p.D60delFs

c.180delC

4 papers

NM_014339.7

p.R66*

c.196C>T

12 papers

NM_014339.7

p.R66Q

c.197G>A

1 paper

NM_014339.7

p.P70R

c.209C>G

2 papers

NM_014339.7

p.K74R

c.221A>G

1 paper

NM_014339.7

p.I78delFs

c.233delT

1 paper

NM_014339.7

p.A83T

c.247G>A

2 papers

NM_014339.7

p.Q86*

c.256C>T

1 paper

NM_014339.7

p.L90L

c.270G>C