Varaico: Literature-Extracted Genetic Variants

IL17RA

243 papers

RefSeq Summary

Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The tran...

Pfam Domains

IL17R_fnIII_D1aa 35–188UCSCIL17RA/B, N-terminal domain

IL17R_fnIII_D2aa 199–303UCSCIL17RD, second fnIII domain

SEFIRaa 378–536UCSCSEFIR domain

Gene Aliases

HGNC Name

interleukin 17 receptor A

HGNC Previous Symbol

IL17R

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014339.7

p.P307_P310del4

c.919_929del12

Surrounding Variants

1 paper

NM_014339.7

p.D308N

c.922G>A

1 paper

NM_014339.7

p.C303_P304insFs

c.909_910insA

1 paper

NM_014339.7

p.P310L

c.929C>T

2 papers

NM_014339.7

p.H297Y

c.889C>T

1 paper

NM_014339.7

p.L295F

c.883C>T

1 paper

NM_014339.7

p.N292K

c.876T>G

15 papers

NM_014339.7

p.Q284*

c.850C>T

1 paper

NM_014339.7

p.I313_P314ins1

c.939_940insAAG

7 papers

NM_014339.7

p.Y316C

c.947A>G

6 papers

NM_014339.7

p.W320R

c.958T>A

6 papers

NM_014339.7

p.W320R

c.958T>C

2 papers

NM_014339.7

p.T326M

c.977C>T