Varaico: Literature-Extracted Genetic Variants

IL17RA

243 papers

RefSeq Summary

Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The tran...

Pfam Domains

IL17R_fnIII_D1aa 35–188UCSCIL17RA/B, N-terminal domain

IL17R_fnIII_D2aa 199–303UCSCIL17RD, second fnIII domain

SEFIRaa 378–536UCSCSEFIR domain

Gene Aliases

HGNC Name

interleukin 17 receptor A

HGNC Previous Symbol

IL17R

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_014339.7

p.E353K

c.1057G>A

Surrounding Variants

1 paper

NM_014339.7

p.S352insFs

c.1054dupA

1 paper

NM_014339.7

p.Y355*

c.1065C>A

1 paper

NM_014339.7

p.Y355*

c.1065C>G

1 paper

NM_014339.7

p.G349Splc

c.1046-2A>G

2 papers

NM_014339.7

p.T359A

c.1075A>G

1 paper

NM_014339.7

p.Y361C

c.1082A>G

1 paper

NM_014339.7

p.D363N

c.1087G>A

1 paper

NM_014339.7

p.A367E

c.1100C>A

11 papers

NM_014339.7

p.A367V

c.1100C>T

1 paper

NM_014339.7

p.D369G

c.1106A>G

1 paper

NM_014339.7

p.I371_V380del10

c.1111_1139del30

1 paper

NM_014339.7

p.P373R

c.1118C>G