Varaico: Literature-Extracted Genetic Variants

IL17RA

243 papers

RefSeq Summary

Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The tran...

Pfam Domains

IL17R_fnIII_D1aa 35–188UCSCIL17RA/B, N-terminal domain

IL17R_fnIII_D2aa 199–303UCSCIL17RD, second fnIII domain

SEFIRaa 378–536UCSCSEFIR domain

Gene Aliases

HGNC Name

interleukin 17 receptor A

HGNC Previous Symbol

IL17R

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_014339.7

p.D387N

c.1159G>A

Surrounding Variants

2 papers

NM_014339.7

p.Y384*

c.1152C>A

2 papers

NM_014339.7

p.Y384*

c.1152C>G

1 paper

NM_014339.7

p.Y384C

c.1151A>G

1 paper

NM_014339.7

p.Y391*

c.1173C>A

1 paper

NM_014339.7

p.Y391*

c.1173C>G

3 papers

NM_014339.7

p.V392L

c.1174G>C

3 papers

NM_014339.7

p.V392L

c.1174G>T

1 paper

NM_014339.7

p.L396delFs

c.1188delG

1 paper

NM_014339.7

p.L396L

c.1188G>A

1 paper

NM_014339.7

p.K376R

c.1127A>G

1 paper

NM_014339.7

p.P373R

c.1118C>G

1 paper

NM_014339.7

p.I371_V380del10

c.1111_1139del30