Varaico: Literature-Extracted Genetic Variants

IL17RA

243 papers

RefSeq Summary

Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The tran...

Pfam Domains

IL17R_fnIII_D1aa 35–188UCSCIL17RA/B, N-terminal domain

IL17R_fnIII_D2aa 199–303UCSCIL17RD, second fnIII domain

SEFIRaa 378–536UCSCSEFIR domain

Gene Aliases

HGNC Name

interleukin 17 receptor A

HGNC Previous Symbol

IL17R

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014339.7

p.E416D

c.1248A>T

Surrounding Variants

1 paper

NM_014339.7

p.E416D

c.1248A>C

1 paper

NM_014339.7

p.L412L

c.1236G>A

1 paper

NM_014339.7

p.A411V

c.1232C>T

1 paper

NM_014339.7

p.E422K

c.1264G>A

1 paper

NM_014339.7

p.G424R

c.1270G>A

1 paper

NM_014339.7

p.G424R

c.1270G>C

1 paper

NM_014339.7

p.R431C

c.1291C>T

1 paper

NM_014339.7

p.Q432E

c.1294C>G

1 paper

NM_014339.7

p.Q434_N440insFs

c.1302_1318dup17

1 paper

NM_014339.7

p.L396L

c.1188G>A

1 paper

NM_014339.7

p.L396delFs

c.1188delG

2 papers

NM_014339.7

p.N440fs

c.1318_1319fs