Varaico: Literature-Extracted Genetic Variants

IL17RA

243 papers

RefSeq Summary

Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The tran...

Pfam Domains

IL17R_fnIII_D1aa 35–188UCSCIL17RA/B, N-terminal domain

IL17R_fnIII_D2aa 199–303UCSCIL17RD, second fnIII domain

SEFIRaa 378–536UCSCSEFIR domain

Gene Aliases

HGNC Name

interleukin 17 receptor A

HGNC Previous Symbol

IL17R

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014339.7

p.V513_G518delFs

c.1537_1553del17

Surrounding Variants

1 paper

NM_014339.7

p.A519A

c.1557G>A

1 paper

NM_014339.7

p.Y523C

c.1568A>G

1 paper

NM_014339.7

p.T498I

c.1493C>T

2 papers

NM_014339.7

p.E531K

c.1591G>A

1 paper

NM_014339.7

p.D489G

c.1466A>G

1 paper

NM_014339.7

p.I486I

c.1458C>T

1 paper

NM_014339.7

p.F542S

c.1625T>C

1 paper

NM_014339.7

p.A482S

c.1444G>T

2 papers

NM_014339.7

p.P544A

c.1630C>G

2 papers

NM_014339.7

p.D477D

c.1431C>T

1 paper

NM_014339.7

p.H471R

c.1412A>G

1 paper

NM_014339.7

p.S554A

c.1660T>G