Varaico: Literature-Extracted Genetic Variants

IL17RA

243 papers

RefSeq Summary

Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The tran...

Pfam Domains

IL17R_fnIII_D1aa 35–188UCSCIL17RA/B, N-terminal domain

IL17R_fnIII_D2aa 199–303UCSCIL17RD, second fnIII domain

SEFIRaa 378–536UCSCSEFIR domain

Gene Aliases

HGNC Name

interleukin 17 receptor A

HGNC Previous Symbol

IL17R

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014339.7

p.L571L

c.1711C>T

Surrounding Variants

2 papers

NM_014339.7

p.A570T

c.1708G>A

1 paper

NM_014339.7

p.Q566fs

c.1696_1697fs

1 paper

NM_014339.7

p.G564D

c.1691G>A

1 paper

NM_014339.7

p.G564S

c.1690G>A

1 paper

NM_014339.7

p.G563D

c.1688G>A

7 papers

NM_014339.7

p.P562Q

c.1685C>A

1 paper

NM_014339.7

p.D583H

c.1747G>C

1 paper

NM_014339.7

p.S554A

c.1660T>G

1 paper

NM_014339.7

p.Y591fs

c.1771_1772fs

1 paper

NM_014339.7

p.S592A

c.1774T>G

1 paper

NM_014339.7

p.S592L

c.1775C>T

2 papers

NM_014339.7

p.P544A

c.1630C>G