Varaico: Literature-Extracted Genetic Variants

IL17RA

243 papers

RefSeq Summary

Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The tran...

Pfam Domains

IL17R_fnIII_D1aa 35–188UCSCIL17RA/B, N-terminal domain

IL17R_fnIII_D2aa 199–303UCSCIL17RD, second fnIII domain

SEFIRaa 378–536UCSCSEFIR domain

Gene Aliases

HGNC Name

interleukin 17 receptor A

HGNC Previous Symbol

IL17R

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

5 papers

NM_014339.7

p.A691T

c.2071G>A

Surrounding Variants

1 paper

NM_014339.7

p.G698E

c.2093G>A

1 paper

NM_014339.7

p.G698G

c.2094G>A

1 paper

NM_014339.7

p.E673E

c.2019G>A

1 paper

NM_014339.7

p.A672T

c.2014G>A

2 papers

NM_014339.7

p.R713*

c.2137C>T

1 paper

NM_014339.7

p.L717F

c.2149C>T

1 paper

NM_014339.7

p.Q663L

c.1988A>T

1 paper

NM_014339.7

p.P720P

c.2160C>G

2 papers

NM_014339.7

p.P720P

c.2160C>T

1 paper

NM_014339.7

p.P727S

c.2179C>T

1 paper

NM_014339.7

p.S731N

c.2192G>A

3 papers

NM_014339.7

p.G643insFs

c.1928_1929insA