Varaico: Literature-Extracted Genetic Variants

Gene:IL18
Variant:p.F170S

IL18

469 papers

RefSeq Summary

The protein encoded by this gene is a proinflammatory cytokine of the IL-1 family that is constitutively found as a precursor within the cytoplasm of a variety of cells including macrophages and kerat...

Pfam Domains

IL1aa 72–185UCSCInterleukin-1 / 18

Gene Aliases

HGNC Name

interleukin 18

HGNC Alias Symbols

IGIF; IL1F4; IL-1g; IL-18

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_001562.4
p.F170S
c.509T>C
Surrounding Variants
1 paper
NM_001562.4
p.F170C
c.509T>G
1 paper
NM_001562.4
p.I173T
c.518T>C
1 paper
NM_001562.4
p.R167T
c.500G>C
1 paper
NM_001562.4
p.C163Y
c.488G>A
1 paper
NM_001562.4
p.C163R
c.487T>C
1 paper
NM_001562.4
p.G158_L161del0
c.472_483del12
1 paper
NM_001562.4
p.A162T
c.484G>A
1 paper
NM_001243211.2
p.E175Q
c.523G>C
1 paper
NM_001562.4
p.L161L
c.481C>T
1 paper
NM_001562.4
p.Y159*
c.477C>G
1 paper
NM_001562.4
p.Y159*
c.477C>A
1 paper
NM_001562.4
p.G158R
c.472G>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."