Varaico: Literature-Extracted Genetic Variants

Gene:IL1B
Variant:p.P173L

IL1B

806 papers

RefSeq Summary

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active ...

Pfam Domains

IL1_propepaa 1–103UCSCInterleukin-1 propeptide
IL1aa 147–264UCSCInterleukin-1 / 18

Gene Aliases

HGNC Name

interleukin 1 beta

HGNC Alias Symbols

IL1F2; IL-1B; IL1-BETA

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000576.3
p.P173L
c.518C>T
Surrounding Variants
1 paper
NM_000576.3
p.I172M
c.516A>G
1 paper
NM_000576.3
p.I172T
c.515T>C
1 paper
NM_000576.3
p.I172V
c.514A>G
1 paper
NM_000576.3
p.A175G
c.524C>G
1 paper
NM_000576.3
p.K171T
c.512A>C
10 papers
NM_000576.3
p.K171E
c.511A>G
2 papers
NM_000576.3
p.K171Q
c.511A>C
1 paper
NM_000576.3
p.D170N
c.508G>A
1 paper
NM_000576.3
p.L178F
c.532C>T
1 paper
NM_000576.3
p.L178V
c.532C>G
1 paper
NM_000576.3
p.S168T
c.503G>C
1 paper
NM_000576.3
p.L178L
c.534C>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."