Varaico: Literature-Extracted Genetic Variants

Gene:IL1B
Variant:p.Q150E

IL1B

806 papers

RefSeq Summary

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active ...

Pfam Domains

IL1_propepaa 1–103UCSCInterleukin-1 propeptide
IL1aa 147–264UCSCInterleukin-1 / 18

Gene Aliases

HGNC Name

interleukin 1 beta

HGNC Alias Symbols

IL1F2; IL-1B; IL1-BETA

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000576.3
p.Q150E
c.448C>G
Surrounding Variants
2 papers
NM_000576.3
p.G149E
c.446G>A
1 paper
NM_000576.3
p.Q148K
c.442C>A
1 paper
NM_000576.3
p.M152T
c.455T>C
4 papers
NM_000576.3
p.L147F
c.439C>T
1 paper
NM_000576.3
p.E153V
c.458A>T
2 papers
NM_000576.3
p.E153G
c.458A>G
4 papers
NM_000576.3
p.Q154*
c.460C>T
1 paper
NM_000576.3
p.H146Y
c.436C>T
1 paper
NM_000576.3
p.L145R
c.434T>G
1 paper
NM_000576.3
p.Q154H
c.462A>T
1 paper
NM_000576.3
p.L145F
c.433C>T
1 paper
NM_000576.3
p.Q155R
c.464A>G
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."