Varaico: Literature-Extracted Genetic Variants

Gene:IL1B
Variant:p.M136I

IL1B

806 papers

RefSeq Summary

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active ...

Pfam Domains

IL1_propepaa 1–103UCSCInterleukin-1 propeptide
IL1aa 147–264UCSCInterleukin-1 / 18

Gene Aliases

HGNC Name

interleukin 1 beta

HGNC Alias Symbols

IL1F2; IL-1B; IL1-BETA

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000576.3
p.M136I
c.408G>C
Surrounding Variants
1 paper
NM_000576.3
p.M136I
c.408G>T
1 paper
NM_000576.3
p.M136I
c.408G>A
1 paper
NM_000576.3
p.S137F
c.410C>T
1 paper
NM_000576.3
p.M136L
c.406A>T
2 papers
NM_000576.3
p.M136V
c.406A>G
1 paper
NM_000576.3
p.M136L
c.406A>C
3 papers
NM_000576.3
p.V135V
c.405G>C
4 papers
NM_000576.3
p.V135M
c.403G>A
2 papers
NM_000576.3
p.L134S
c.401T>C
1 paper
NM_000576.3
p.P139A
c.415C>G
1 paper
NM_000576.3
p.L134V
c.400T>G
2 papers
NM_000576.3
p.E141D
c.423A>T
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."