Varaico: Literature-Extracted Genetic Variants

Gene:IL1B
Variant:p.L126R

IL1B

806 papers

RefSeq Summary

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active ...

Pfam Domains

IL1_propepaa 1–103UCSCInterleukin-1 propeptide
IL1aa 147–264UCSCInterleukin-1 / 18

Gene Aliases

HGNC Name

interleukin 1 beta

HGNC Alias Symbols

IL1F2; IL-1B; IL1-BETA

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000576.3
p.L126R
c.377T>G
Surrounding Variants
1 paper
NM_000576.3
p.T125_L126del1
c.374_376delGCG
2 papers
NM_000576.3
p.R127W
c.379C>T
1 paper
NM_000576.3
p.R127Q
c.380G>A
1 paper
NM_000576.3
p.T125M
c.374C>T
1 paper
NM_000576.3
p.T125A
c.373A>G
1 paper
NM_000576.3
p.D128Y
c.382G>T
1 paper
NM_000576.3
p.C124C
c.372C>T
1 paper
NM_000576.3
p.C124S
c.371G>C
1 paper
NM_000576.3
p.N123_C124delFs
c.369_370delAG
1 paper
NM_000576.3
p.D128G
c.383A>G
1 paper
NM_000576.3
p.C124S
c.370T>A
2 papers
NM_000576.3
p.S129T
c.385T>A
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