Varaico: Literature-Extracted Genetic Variants

Gene:IL1B
Variant:p.T92I

IL1B

806 papers

RefSeq Summary

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active ...

Pfam Domains

IL1_propepaa 1–103UCSCInterleukin-1 propeptide
IL1aa 147–264UCSCInterleukin-1 / 18

Gene Aliases

HGNC Name

interleukin 1 beta

HGNC Alias Symbols

IL1F2; IL-1B; IL1-BETA

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
4 papers
NM_000576.3
p.T92I
c.275C>T
Surrounding Variants
1 paper
NM_000576.3
p.T92S
c.275C>G
1 paper
NM_000576.3
p.S91R
c.273C>G
1 paper
NM_000576.3
p.S91R
c.273C>A
1 paper
NM_000576.3
p.S91T
c.272G>C
1 paper
NM_000576.3
p.S91R
c.271A>C
1 paper
NM_000576.3
p.L90P
c.269T>C
1 paper
NM_000576.3
p.L90M
c.268C>A
1 paper
NM_000576.3
p.D89N
c.265G>A
1 paper
NM_000576.3
p.P95P
c.285C>G
1 paper
NM_000576.3
p.F96F
c.288C>T
1 paper
NM_000576.3
p.I97F
c.289A>T
1 paper
NM_000576.3
p.F98I
c.292T>A
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