Varaico: Literature-Extracted Genetic Variants

Gene:IL1B
Variant:p.H56D

IL1B

806 papers

RefSeq Summary

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active ...

Pfam Domains

IL1_propepaa 1–103UCSCInterleukin-1 propeptide
IL1aa 147–264UCSCInterleukin-1 / 18

Gene Aliases

HGNC Name

interleukin 1 beta

HGNC Alias Symbols

IL1F2; IL-1B; IL1-BETA

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000576.3
p.H56D
c.166C>G
Surrounding Variants
1 paper
NM_000576.3
p.H56Y
c.166C>T
1 paper
NM_000576.3
p.H56Q
c.168C>G
1 paper
NM_000576.3
p.H56Q
c.168C>A
1 paper
NM_000576.3
p.H55R
c.164A>G
1 paper
NM_000576.3
p.Y57Y
c.171C>T
1 paper
NM_000576.3
p.D54H
c.160G>C
1 paper
NM_000576.3
p.D54N
c.160G>A
7 papers
NM_000576.3
p.S58T
c.173G>C
2 papers
NM_000576.3
p.S53S
c.159C>T
8 papers
NM_000576.3
p.S58R
c.174C>G
1 paper
NM_000576.3
p.S53Y
c.158C>A
1 paper
NM_000576.3
p.K59E
c.175A>G
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."