Varaico: Literature-Extracted Genetic Variants

Gene:IL1B
Variant:p.E10D

IL1B

806 papers

RefSeq Summary

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active ...

Pfam Domains

IL1_propepaa 1–103UCSCInterleukin-1 propeptide
IL1aa 147–264UCSCInterleukin-1 / 18

Gene Aliases

HGNC Name

interleukin 1 beta

HGNC Alias Symbols

IL1F2; IL-1B; IL1-BETA

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000576.3
p.E10D
c.30A>T
Surrounding Variants
1 paper
NM_000576.3
p.E10D
c.30A>C
1 paper
NM_000576.3
p.E10V
c.29A>T
3 papers
NM_000576.3
p.M11V
c.31A>G
1 paper
NM_000576.3
p.M11T
c.32T>C
2 papers
NM_000576.3
p.E10K
c.28G>A
1 paper
NM_000576.3
p.M11I
c.33G>A
1 paper
NM_000576.3
p.M12L
c.34A>C
1 paper
NM_000576.3
p.M12R
c.35T>G
4 papers
NM_000576.3
p.M12T
c.35T>C
1 paper
NM_000576.3
p.S9G
c.25A>G
1 paper
NM_000576.3
p.M12I
c.36G>C
1 paper
NM_000576.3
p.A13T
c.37G>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."