Varaico: Literature-Extracted Genetic Variants

IL1R1

225 papers

RefSeq Summary

This gene encodes a cytokine receptor that belongs to the interleukin-1 receptor family. The encoded protein is a receptor for interleukin-1 alpha, interleukin-1 beta, and interleukin-1 receptor antag...

Pfam Domains

Ig_6aa 18–126UCSCImmunoglobulin domain

Ig_2aa 123–213UCSCImmunoglobulin domain

Gene Aliases

HGNC Name

interleukin 1 receptor type 1

HGNC Previous Symbol

IL1RA

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000877.4

p.V134A

c.401T>C

Surrounding Variants

1 paper

NM_000877.4

p.L132L

c.394C>T

1 paper

NM_000877.4

p.K131R

c.392A>G

2 papers

NM_000877.4

p.K131E

c.391A>G

1 paper

NM_000877.4

p.G138R

c.412G>C

1 paper

NM_000877.4

p.G139*

c.415G>T

1 paper

NM_000877.4

p.K129insFs

c.386dupA

1 paper

NM_000877.4

p.V141L

c.421G>C

4 papers

NM_000877.4

p.Q125K

c.373C>A

10 papers

NM_000877.4

p.A124G

c.371C>G

1 paper

NM_000877.4

p.E117E

c.351G>A

1 paper

NM_000877.4

p.L155insFs

c.464_465insT

1 paper

NM_000877.4

p.L158_Y161del0

c.472_483del12