Varaico: Literature-Extracted Genetic Variants

Gene:IL1RN
Variant:p.R122C

IL1RN

449 papers

RefSeq Summary

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a v...

Pfam Domains

IL1aa 60–173UCSCInterleukin-1 / 18

Gene Aliases

HGNC Name

interleukin 1 receptor antagonist

HGNC Alias Symbols

IL1RA; ICIL-1RA; IL1F3; IRAP; IL-1RN; MGC10430

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_173842.3
p.R122C
c.364C>T
Surrounding Variants
1 paper
NM_173842.3
p.R122H
c.365G>A
1 paper
NM_173842.3
p.K121E
c.361A>G
1 paper
NM_173842.3
p.D120G
c.359A>G
1 paper
NM_173842.3
p.F123F
c.369C>T
3 papers
NM_173842.3
p.A124T
c.370G>A
1 paper
NM_173842.3
p.A124G
c.371C>G
9 papers
NM_173842.3
p.Q119*
c.355C>T
NM_173841.3
p.Q122*
c.364C>T
1 paper
NM_173842.3
p.I126V
c.376A>G
1 paper
NM_173842.3
p.K118*
c.352A>T
1 paper
NM_173842.3
p.R117R
c.351A>G
2 papers
NM_173842.3
p.N116S
c.347A>G
1 paper
NM_173842.3
p.E115D
c.345G>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."