Varaico: Literature-Extracted Genetic Variants

Gene:IL21
Variant:p.R139*

IL21

124 papers

RefSeq Summary

This gene encodes a member of the common-gamma chain family of cytokines with immunoregulatory activity. The encoded protein plays a role in both the innate and adaptive immune responses by inducing t...

Pfam Domains

IL15aa 11–149UCSCInterleukin 15

Gene Aliases

HGNC Name

interleukin 21

HGNC Alias Symbols

Za11; IL-21

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_021803.4
p.R139*
c.415A>T
Surrounding Variants
1 paper
NM_021803.4
p.D126N
c.376G>A
1 paper
NM_021803.4
p.P123R
c.368C>G
1 paper
NM_021803.4
p.C122*
c.366C>A
3 papers
NM_021803.4
p.H149Y
c.445C>T
1 paper
NM_021803.4
p.H157L
c.470A>T
1 paper
NM_021803.4
p.G158A
c.473G>C
1 paper
NM_021803.4
p.G158_D161del0
c.472_483del12
1 paper
NM_021803.4
p.*163*
c.488G>A
1 paper
NM_021803.4
p.Q116L
c.347A>T
1 paper
NM_021803.4
p.Q116R
c.347A>G
1 paper
NM_021803.4
p.Q116K
c.346C>A
1 paper
NM_021803.4
p.G113A
c.338G>C
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