Varaico: Literature-Extracted Genetic Variants

Gene:IL27RA
Variant:p.L188P

IL27RA

81 papers

RefSeq Summary

In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells, which are critical for cell-mediated immunity, predominantly under the influence of IL12. Also, IL4 influences their differentiation...

Pfam Domains

IL27RA_FN3_3aa 237–314UCSCIL27RA third fibronectin type-III domain

Gene Aliases

HGNC Name

interleukin 27 receptor subunit alpha

HGNC Alias Symbols

WSX-1; TCCR; CRL1; WSX1; zcytor1; IL-27R

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
3 papers
NM_004843.4
p.L188P
c.563T>C
Surrounding Variants
1 paper
NM_004843.4
p.P190S
c.568C>T
1 paper
NM_004843.4
p.P181L
c.542C>T
1 paper
NM_004843.4
p.G201V
c.602G>T
1 paper
NM_004843.4
p.R209W
c.625C>T
1 paper
NM_004843.4
p.P222L
c.665C>T
1 paper
NM_004843.4
p.G248R
c.742G>A
1 paper
NM_004843.4
p.G248R
c.742G>C
1 paper
NM_004843.4
p.W255R
c.763T>A
1 paper
NM_004843.4
p.W255R
c.763T>C
1 paper
NM_004843.4
p.W255*
c.765G>A
1 paper
NM_004843.4
p.S158_V161del0
c.472_483del12
1 paper
NM_004843.4
p.P154_T155delFs
c.462_463delTA
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