Varaico: Literature-Extracted Genetic Variants

Gene:IL27RA
Variant:p.T421M

IL27RA

81 papers

RefSeq Summary

In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells, which are critical for cell-mediated immunity, predominantly under the influence of IL12. Also, IL4 influences their differentiation...

Pfam Domains

IL27RA_FN3_3aa 237–314UCSCIL27RA third fibronectin type-III domain

Gene Aliases

HGNC Name

interleukin 27 receptor subunit alpha

HGNC Alias Symbols

WSX-1; TCCR; CRL1; WSX1; zcytor1; IL-27R

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_004843.4
p.T421M
c.1262C>T
Surrounding Variants
1 paper
NM_004843.4
p.W423*
c.1268G>A
1 paper
NM_004843.4
p.W423*
c.1269G>A
1 paper
NM_004843.4
p.V418G
c.1253T>G
1 paper
NM_004843.4
p.A434T
c.1300G>A
1 paper
NM_004843.4
p.R446G
c.1336C>G
1 paper
NM_004843.4
p.P462_S463del2
c.1384_1388del6
1 paper
NM_004843.4
p.P462_S463delFs
c.1384_1387del4
1 paper
NM_004843.4
p.G400fs
c.1198_1199fs
1 paper
NM_004843.4
p.G400_E412delFs
c.1200_1234del35
1 paper
NM_004843.4
p.A395del1
c.1183_1184delGCA
1 paper
NM_004843.4
p.P388L
c.1163C>T
1 paper
NM_004843.4
p.V385V
c.1155C>T
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