Varaico: Literature-Extracted Genetic Variants

Gene:IL2RB
Variant:p.R523G

IL2RB

377 papers

RefSeq Summary

The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha ...

Pfam Domains

IL2RB_N1aa 32–123UCSCInterleukin-2 receptor subunit beta N-terminal domain 1

Gene Aliases

HGNC Name

interleukin 2 receptor subunit beta

HGNC Previous Symbol

IL15RB

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000878.5
p.R523G
c.1567A>G
Surrounding Variants
1 paper
NM_000878.5
p.L525_N526del2
c.1573_1577del6
1 paper
NM_000878.5
p.P512P
c.1536C>A
1 paper
NM_000878.5
p.R506G
c.1516A>G
1 paper
NM_000878.5
p.Q545*
c.1633C>T
1 paper
NM_000878.5
p.E499K
c.1495G>A
1 paper
NM_000878.5
p.P547S
c.1639C>T
1 paper
NM_000878.5
p.P547R
c.1640C>G
1 paper
NM_000878.5
p.L472_V483del12
c.1414_1448del36
1 paper
NM_000878.5
p.T476delins
c.1427_1428delinsTG
1 paper
NM_000878.5
p.P464L
c.1391C>T
1 paper
NM_000878.5
p.A450T
c.1348G>A
2 papers
NM_000878.5
p.G446R
c.1336G>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."