Varaico: Literature-Extracted Genetic Variants

Gene:IL2RB
Variant:p.R424_L427del4

IL2RB

377 papers

RefSeq Summary

The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha ...

Pfam Domains

IL2RB_N1aa 32–123UCSCInterleukin-2 receptor subunit beta N-terminal domain 1

Gene Aliases

HGNC Name

interleukin 2 receptor subunit beta

HGNC Previous Symbol

IL15RB

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000878.5
p.R424_L427del4
c.1270_1280del12
Surrounding Variants
1 paper
NM_000878.5
p.L429F
c.1285C>T
1 paper
NM_000878.5
p.D416N
c.1246G>A
1 paper
NM_000878.5
p.P440S
c.1318C>T
1 paper
NM_000878.5
p.P440L
c.1319C>T
1 paper
NM_000878.5
p.P441fs
c.1321_1322fs
1 paper
NM_000878.5
p.P410R
c.1229C>G
2 papers
NM_000878.5
p.G446R
c.1336G>C
2 papers
NM_000878.5
p.G446R
c.1336G>A
1 paper
NM_000878.5
p.A450T
c.1348G>A
1 paper
NM_000878.5
p.G402E
c.1205G>A
1 paper
NM_000878.5
p.G398R
c.1192G>A
1 paper
NM_000878.5
p.A397_G398insFs
c.1191_1192insG
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."