Varaico: Literature-Extracted Genetic Variants

Gene:IL2RB
Variant:p.L77H

IL2RB

377 papers

RefSeq Summary

The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha ...

Pfam Domains

IL2RB_N1aa 32–123UCSCInterleukin-2 receptor subunit beta N-terminal domain 1

Gene Aliases

HGNC Name

interleukin 2 receptor subunit beta

HGNC Previous Symbol

IL15RB

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000878.5
p.L77H
c.230T>A
Surrounding Variants
3 papers
NM_000878.5
p.L77P
c.230T>C
1 paper
NM_000878.5
p.L76delFs
c.227delA
2 papers
NM_000878.5
p.V79M
c.235G>A
1 paper
NM_000878.5
p.C74S
c.221G>C
1 paper
NM_000878.5
p.A92G
c.275C>G
1 paper
NM_000878.5
p.R67K
c.200G>A
1 paper
NM_000878.5
p.D66A
c.197A>C
1 paper
NM_000878.5
p.D66N
c.196G>A
1 paper
NM_000878.5
p.C59W
c.177C>G
1 paper
NM_000878.5
p.L54M
c.160C>A
1 paper
NM_000878.5
p.A53T
c.157G>A
1 paper
NM_000878.5
p.D51A
c.152A>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."