Varaico: Literature-Extracted Genetic Variants

Gene:IL4
Variant:p.R109Q

IL4

634 papers

RefSeq Summary

The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may...

Pfam Domains

IL4aa 26–92UCSCInterleukin 4
IL4aa 26–149UCSCInterleukin 4

Gene Aliases

HGNC Name

interleukin 4

HGNC Alias Symbols

BSF1; IL-4; BCGF1; BCGF-1; MGC79402

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
4 papers
NM_000589.4
p.R109Q
c.326G>A
Surrounding Variants
1 paper
NM_000589.4
p.R109L
c.326G>T
2 papers
NM_000589.4
p.R109W
c.325C>T
1 paper
NM_000589.4
p.L110F
c.328C>T
1 paper
NM_000589.4
p.L110P
c.329T>C
1 paper
NM_000589.4
p.K108E
c.322A>G
1 paper
NM_000589.4
p.D111N
c.331G>A
2 papers
NM_000589.4
p.L107V
c.319C>G
2 papers
NM_000589.4
p.D111D
c.333C>T
1 paper
NM_000589.4
p.L107L
c.319C>T
5 papers
NM_000589.4
p.R112W
c.334A>T
9 papers
NM_000589.4
p.F106F
c.318C>T
1 paper
NM_000589.4
p.R112K
c.335G>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."