Varaico: Literature-Extracted Genetic Variants

Gene:IL4R
Variant:p.E400A

IL4R

559 papers

RefSeq Summary

This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can ...

Pfam Domains

IL4Ra_Naa 28–121UCSCInterleukin-4 receptor alpha chain, N-terminal

Gene Aliases

HGNC Name

interleukin 4 receptor

HGNC Alias Symbol

CD124

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
33 papers
NM_000418.4
p.E400A
c.1199A>C
Surrounding Variants
1 paper
NM_000418.4
p.V403V
c.1209G>A
1 paper
NM_000418.4
p.A404T
c.1210G>A
2 papers
NM_000418.4
p.S387S
c.1161G>A
3 papers
NM_000418.4
p.S387L
c.1160C>T
3 papers
NM_000418.4
p.L414L
c.1242G>T
1 paper
NM_000418.4
p.G382E
c.1145G>A
1 paper
NM_000418.4
p.G382R
c.1144G>A
1 paper
NM_000418.4
p.G382R
c.1144G>C
1 paper
NM_000418.4
p.G421delFs
c.1262delG
1 paper
NM_000418.4
p.G420R
c.1258G>A
1 paper
NM_000418.4
p.G421G
c.1263C>A
1 paper
NM_000418.4
p.F422L
c.1264T>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."