Varaico: Literature-Extracted Genetic Variants

Gene:IL4R
Variant:p.I638I

IL4R

559 papers

RefSeq Summary

This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can ...

Pfam Domains

IL4Ra_Naa 28–121UCSCInterleukin-4 receptor alpha chain, N-terminal

Gene Aliases

HGNC Name

interleukin 4 receptor

HGNC Alias Symbol

CD124

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
4 papers
NM_000418.4
p.I638I
c.1914T>C
Surrounding Variants
1 paper
NM_000418.4
p.C641C
c.1923C>T
2 papers
NM_000418.4
p.Q635*
c.1903C>T
1 paper
NM_000418.4
p.Y631C
c.1892A>G
1 paper
NM_000418.4
p.A646V
c.1937C>T
1 paper
NM_000418.4
p.K619R
c.1856A>G
1 paper
NM_000418.4
p.D658G
c.1973A>G
1 paper
NM_000418.4
p.V615V
c.1845G>A
1 paper
NM_000418.4
p.Q666*
c.1996C>T
1 paper
NM_000418.4
p.Q666L
c.1997A>T
1 paper
NM_000418.4
p.L610I
c.1828C>A
1 paper
NM_000418.4
p.L610F
c.1828C>T
4 papers
NM_000418.4
p.P675S
c.2023C>T
NM_001257997.2
p.P515S
c.1543C>T
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."