Varaico: Literature-Extracted Genetic Variants

Gene:IL6
Variant:p.F4C

IL6

3,892 papers

RefSeq Summary

This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in peop...

Pfam Domains

IL6aa 27–212UCSCInterleukin-6/G-CSF/MGF family

Gene Aliases

HGNC Name

interleukin 6

HGNC Previous Symbol

IFNB2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
3 papers
NM_000600.5
p.F4C
c.11T>G
Surrounding Variants
1 paper
NM_000600.5
p.F4Y
c.11T>A
6 papers
NM_000600.5
p.F4L
c.10T>C
1 paper
NM_000600.5
p.F4V
c.10T>G
1 paper
NM_000600.5
p.S5P
c.13T>C
1 paper
NM_000600.5
p.S3Y
c.8C>A
1 paper
NM_000600.5
p.S5Y
c.14C>A
3 papers
NM_000600.5
p.S5F
c.14C>T
1 paper
NM_000600.5
p.S5S
c.15C>A
1 paper
NM_000600.5
p.S3T
c.7T>A
2 papers
NM_000600.5
p.S3delFs
c.8delC
2 papers
NM_000600.5
p.T6A
c.16A>G
1 paper
NM_000600.5
p.N2K
c.6C>A
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