Varaico: Literature-Extracted Genetic Variants

Gene:IL6
Variant:p.S7Splc

IL6

3,892 papers

RefSeq Summary

This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in peop...

Pfam Domains

IL6aa 27–212UCSCInterleukin-6/G-CSF/MGF family

Gene Aliases

HGNC Name

interleukin 6

HGNC Previous Symbol

IFNB2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000600.5
p.S7Splc
c.20-2A>T
Surrounding Variants
1 paper
NM_000600.5
p.S7Splc
c.20-1G>T
5 papers
NM_000600.5
p.S7N
c.20G>A
1 paper
NM_000600.5
p.S7delins
c.20delinsC
1 paper
NM_000600.5
p.S7R
c.21C>A
2 papers
NM_000600.5
p.S7S
c.21C>T
2 papers
NM_000600.5
p.A8T
c.22G>A
2 papers
NM_000600.5
p.A8P
c.22G>C
1 paper
NM_000600.5
p.A8S
c.22G>T
1 paper
NM_000600.5
p.F9S
c.26T>C
1 paper
NM_000600.5
p.G10delFs
c.28delG
2 papers
NM_000600.5
p.G10S
c.28G>A
1 paper
NM_000600.5
p.G10R
c.28G>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."