Varaico: Literature-Extracted Genetic Variants

Gene:IL6
Variant:p.S15insFs

IL6

3,892 papers

RefSeq Summary

This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in peop...

Pfam Domains

IL6aa 27–212UCSCInterleukin-6/G-CSF/MGF family

Gene Aliases

HGNC Name

interleukin 6

HGNC Previous Symbol

IFNB2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000600.5
p.S15insFs
c.45dupC
Surrounding Variants
1 paper
NM_000600.5
p.F14L
c.42C>A
5 papers
NM_000600.5
p.S15C
c.44C>G
2 papers
NM_000600.5
p.L16del1
c.46_47delCTG
1 paper
NM_000600.5
p.L16L
c.46C>T
1 paper
NM_000600.5
p.F14I
c.40T>A
1 paper
NM_000600.5
p.G17insFs
c.50dupG
1 paper
NM_000600.5
p.F14del1
c.40_41delTTC
1 paper
NM_000600.5
p.L16L
c.48G>A
1 paper
NM_000600.5
p.G17R
c.49G>A
1 paper
NM_000600.5
p.V12V
c.36T>C
1 paper
NM_000600.5
p.L18M
c.52C>A
1 paper
NM_000600.5
p.L18insFs
c.53_54insT
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